Methoxyphosphonous Dichloride
methyl dichlorophosphite
CAS: 3279-26-3
Molecular Formula: CH3Cl2OP
Methoxyphosphonous Dichloride - Names and Identifiers
Methoxyphosphonous Dichloride - Physico-chemical Properties
| Molecular Formula | CH3Cl2OP |
| Molar Mass | 132.91 |
| Density | 1.376 g/mL at 20 °C (lit.) |
| Melting Point | -91 °C (lit.) |
| Boling Point | 93-95 °C (lit.) |
| Flash Point | 104°F |
| Water Solubility | Reacts with water. Soluble in chloroform, dichloromethane and ethyl acetate. |
| Vapor Presure | 66.3mmHg at 25°C |
| Appearance | liquid |
| Color | Colorless to Almost colorless |
| BRN | 1697452 |
| Storage Condition | −20°C |
| Stability | Flammable. |
| Sensitive | Moisture Sensitive |
| Refractive Index | n20/D 1.474(lit.) |
| MDL | MFCD00000524 |
Methoxyphosphonous Dichloride - Risk and Safety
| Hazard Symbols | C - Corrosive |
| Risk Codes | R10 - Flammable R14 - Reacts violently with water R34 - Causes burns R37 - Irritating to the respiratory system |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2920 8/PG 2 |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10-13-23 |
| HS Code | 29209090 |
| Hazard Class | 8 |
| Packing Group | II |
Methoxyphosphonous Dichloride - Introduction
methyl dichlorophosphite is an organic compound with the chemical formula CH3OCl2P. It is a colorless liquid, insoluble in water at room temperature, but soluble in organic solvents such as ether and benzene.
methyl dichlorophosphite has a wide range of applications in organic synthesis. It can be used as a synthetic reagent of phosphine compounds for the synthesis of various organophosphorus compounds. In addition, it can also be used as an alkylating agent for phosphate esters for the synthesis of drugs, pesticides and other organic compounds.
A common method for preparing methyl dichlorophosphite is to react phosphine dichloride with methanol. The reaction conditions may be room temperature, and the reaction is promoted by an acid-base catalyst such as aluminum trichloride or the like.
Pay attention to safety when using methyl dichlorophosphite. It is an organic phosphine compound with certain toxicity and irritation. Contact with skin, eyes or inhalation of its vapors may cause irritation and injury. The operation should be carried out in a well-ventilated environment with appropriate protective equipment such as gloves, glasses and masks. At the same time, it should be stored in a sealed container, away from heat and fire sources. If ingested or inhaled, seek medical help immediately.
methyl dichlorophosphite has a wide range of applications in organic synthesis. It can be used as a synthetic reagent of phosphine compounds for the synthesis of various organophosphorus compounds. In addition, it can also be used as an alkylating agent for phosphate esters for the synthesis of drugs, pesticides and other organic compounds.
A common method for preparing methyl dichlorophosphite is to react phosphine dichloride with methanol. The reaction conditions may be room temperature, and the reaction is promoted by an acid-base catalyst such as aluminum trichloride or the like.
Pay attention to safety when using methyl dichlorophosphite. It is an organic phosphine compound with certain toxicity and irritation. Contact with skin, eyes or inhalation of its vapors may cause irritation and injury. The operation should be carried out in a well-ventilated environment with appropriate protective equipment such as gloves, glasses and masks. At the same time, it should be stored in a sealed container, away from heat and fire sources. If ingested or inhaled, seek medical help immediately.
Last Update：2024-04-09 21:11:58
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